Anthropic reports 85.1% for Claude Mythos 5.2 on de novo binder design (24-hour setting). Anthropic lists it under protein design.
Tasks: 24-hour setting, as labeled; protein design.
Setting: Highest-available effort, per the table footnote; the effort level is not named for this row. Numeric reasoning and token budgets are not stated.
Limits: Provider-reported by Anthropic in its launch announcement; not independently reproduced here. Anthropic points to the Fable 5.2 and Mythos 5.2 system card for methods; that card was not opened, so task subset, sample size, harness, prompts, trial counts and run dates are unverified. Results under the same benchmark name can be shown together as reported scores, but unmatched settings and missing methods rule out a controlled ranking. What the percentage measures is not explained on the announcement.
Anthropic